HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Bromomethyl)-2-fluoro-1-methoxybenzene → HCID 71209257, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Bromomethyl)-2-fluoro-1-methoxybenzene | HCID 2774553 | — |
| Reactant | methyl 2-(tert-butoxy)-2-(4-(chroman-6-yl)-6-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)acetate | HCID 71209024 | — |
| Product | HCID 71209257 | HCID 71209257 | — |
Reaction Steps
The title compound was prepared in a manner similar to that described in Example 27, Step H from methyl 2-(tert-butoxy)-2-(4-(chroman-6-yl)-6-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)acetate and 3-fluoro-4-methoxybenzyl bromide. 1H NMR (400 MHz, CHLOROFORM-d) δ ppm 7.51-7.41 (m, 1 H), 7.25-7.18 (m, 1 H), 7.07-6.99 (m, 3 H), 6.97-6.88 (m, 2 H), 6.31-6.23 (m, 1 H), 5.63-5.56 (m, 1 H), 5.53-5.36 (m, 2 H), 4.32-4.26 (m, 2 H), 3.90-3.86 (m, 3 H), 2.96-2.80 (m, 2 H), 2.75 (s, 3 H), 2.14-2.04 (m, 2 H), 0.97 (s, 9H); LC/MS (m/z) ES+=533.28 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609653B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-93436bfcbacd4c6d89751ce9309739c9 |
| Source note | uspto-grants-2013_12 |