1-Bromomethyl-2,6-dichlorobenzene → HCID 71209252, compound

Participants

Reaction Steps

The title compound was prepared in a manner similar to that described in Example 27, Step H from methyl 2-(tert-butoxy)-2-(4-(chroman-6-yl)-6-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)acetate and 2,6-dichlorobenzyl bromide. 1H NMR (400 MHz, CHLOROFORM-d) δ ppm 7.49-7.37 (m, 3 H), 7.28-7.21 (m, 2 H), 6.91 (t, J=8.3 Hz, 1 H), 6.83-6.78 (m, 1 H), 6.19-6.13 (m, 1 H), 5.83-5.68 (m, 2 H), 5.62-5.56 (m, 1 H), 4.27 (t, J=5.2 Hz, 2 H), 2.94-2.77 (m, 2 H), 2.75 (s, 3 H), 2.12-2.06 (m, 2 H), 0.97 (s, 9 H); LC/MS (m/z) ES+=553.30 (M+1).

Provenance & Evidence