2-Chloro-6-fluorobenzyl bromide → HCID 71209370, compound

Participants

Reaction Steps

The title compound was prepared in a manner similar to that described in Example 27, Step H from methyl 2-(tert-butoxy)-2-(4-(chroman-6-yl)-6-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)acetate and 2-chloro-6-fluorobenzyl bromide. 1H NMR (400 MHz, CHLOROFORM-d) δ ppm 7.48-7.40 (m, 1 H), 7.33-7.27 (m, 2 H), 7.23-7.17 (m, 1 H), 7.10-7.03 (m, 1 H), 7.00-6.95 (m, 1 H), 6.91 (t, J=7.7 Hz, 1 H), 6.21-6.14 (m, 1 H), 5.72-5.55 (m, 3 H), 4.31-4.24 (m, 2 H), 2.92-2.77 (m, 2 H), 2.74 (s, 3 H), 2.06 (s, 2 H), 1.02-0.92 (s, 9 H); LC/MS (m/z) ES+=537.38 (M+1).

Provenance & Evidence