3-Methoxybenzyl bromide → HCID 71208959, compound

Participants

Reaction Steps

The title compound was prepared in a manner similar to that described in Example 27, Step H from methyl 2-(tert-butoxy)-2-(4-(chroman-6-yl)-6-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)acetate and 3-methoxybenzyl bromide. 1H NMR (400 MHz, CHLOROFORM-d) δ ppm 7.51-7.43 (m, 1 H), 7.27-7.17 (m, 2 H), 7.09-7.04 (m, 1 H), 6.96-6.91 (m, 1 H), 6.89-6.81 (m, 3 H), 6.28 (dd, J=3.5, 10.9 Hz, 1 H), 5.62-5.43 (m, 3 H), 4.33-4.25 (m, 2 H), 3.78 (d, J=1.2 Hz, 3 H), 2.96-2.80 (m, 2 H), 2.78 (s, 3 H), 2.15-2.03 (m, 2 H), 1.02-0.91 (s, 9 H); LC/MS (m/z) ES+=515.38 (M+1).

Provenance & Evidence