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HRID1912670

反应详情

EQUATION

反应方程式

HRID 1912670 的结构方程式

REACTANTS

反应物

2
结构：C[C@]12CC[C@H]3[C@@H](CC(=O)C4C[C@@H](O)CC[C@@]43C)[C@@H]1CC[C@@H]2O
HCID12158920

未命名化合物

结构：C[C@]12CCCCC1=CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC13OCCOC12OCCO3
HCID86651495

未命名化合物

PRODUCTS

生成物

1
结构：C[C@]12CC[C@H]3[C@@H](CC4(OCCO4)C4C[C@@H](O)CC[C@@]43C)[C@@H]1CC[C@@H]2O
HCID69133411

未命名化合物

收率 70%

PROCEDURE

实验过程

6,6-Ethylendioxyandrostane-3β,17β-diol was prepared in 70% yield from 3β,17β-dihydroxyandrostan-6-one by the procedure described above for the preparation of 3,3:17,17-bis(ethylendioxy)-5-androstene (Prepn. 5). The combined organic extracts were washed with H2O, dried over Na2SO4 and evaporated to dryness to give 6,6-ethylendioxyandrostane-3β,17β-diol. 1H-NMR (300 MHz, DMSO-d6, ppm from TMS): δ 4.45 (d, 1H), 4.41 (d, 1H), 3.90-3.57 (m, 4H), 3.41 (m, 1H), 3.29 (m, 1H), 1.87-0.53 (m, 20H), 0.84 (s, 3H), 0.60 (s, 3H).

WORKUP

后处理

  1. customdescribed above for the preparation of 3,3
  2. washThe combined organic extracts were washed with H2O
  3. dry with materialdried over Na2SO4
  4. customevaporated to dryness
  5. customto give 6,6-ethylendioxyandrostane-3β,17β-diol