HRID1912679

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C[C@]12CCC(=O)CC1[C@@H](C#N)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12

HCID69133284

未命名化合物

结构：C[C@]12CCCCC1[C@@H](CO)C[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC13OCCOC12OCCO3

HCID86635564

未命名化合物

PRODUCTS

生成物

结构：C[C@]12CCC(=O)CC1[C@@H](CO)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12

HCID69010824

未命名化合物

收率 85%

PROCEDURE

实验过程

The title compound II-an was prepared in 85% yield from 3,3:17,17-bis(ethylendioxy)-6α-hydroxymethylandrostane by the procedure described above for the preparation of 6α-cyanoandrostane-3,17-dione (II-ac, Prepn. 3). The combined organic extracts were washed with H2O, dried over Na2SO4 and evaporated to dryness. 1H-NMR (300 MHz, acetone-d6, ppm from TMS): δ 3.50 (m, 3H), 2.52-0.74 (m, 21H), 1.11 (s, 3H), 0.88 (s, 3H).

WORKUP

后处理

washThe combined organic extracts were washed with H2O
dry with materialdried over Na2SO4
customevaporated to dryness