HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69133284, compound → (6E,8R,9S,10R,13S,14S)-6-ethoxyimino-10,13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69133284 | HCID 69133284 | — |
| Reactant | (E,2S,5S,6R,14R,15S)-N-ethoxy-2,6-dimethyl-18,21,22,25-tetraoxahexacyclo[15.4.4.01,17.02,15.05,14.06,11]pentacosan-12-imine | HCID 178474300 | — |
| Product | (6E,8R,9S,10R,13S,14S)-6-ethoxyimino-10,13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-dione | HCID 87709931 | 100% |
Reaction Steps
The title compound II-av was prepared in 100% yield from 3,3:17,17-bis(ethylendioxy)-6(E)-ethoxyiminoandrostane by the procedure described above for the preparation of 6α-cyanoandrostane-3,17-dione (II-ac, Prepn. 3). The combined organic extracts were washed with H2O, dried over Na2SO4 and evaporated to dryness. 1H-NMR (300 MHz, acetone-d6, ppm from TMS): δ 4.03 (2H, q), 3.40 (1H, dd), 2.70-1.12 (19H, m), 1.20 (3H, t), 1.01 (3H, s), 0.87 (3H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609644B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-9dee7afe7da3497689687a0d33ea9e72 |
| Source note | uspto-grants-2013_12 |