HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69133284, compound → 6-Difluoromethyleneandrostane-3,17-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69133284 | HCID 69133284 | — |
| Reactant | 17,17-Bis(ethylendioxy)-6-difluoromethyleneandrostane | HCID 86635571 | — |
| Product | 6-Difluoromethyleneandrostane-3,17-dione | HCID 67535780 | 99% |
Reaction Steps
The title compound II-bf was prepared in 99% yield from 3,3:17,17-bis(ethylendioxy)-6-difluoromethyleneandrostane by the procedure described above for the preparation of 6α-cyanoandrostane-3,17-dione (II-ac, Prepn. 3). The combined organic extracts were washed with H2O, dried over Na2SO4 and evaporated to dryness. 1H-NMR (300 MHz, acetone-d6, ppm from TMS): δ 2.85-0.95 (m, 20H), 1.12 (s, 3H), 0.88 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609644B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-188e8736ed1f41508f50b8cdf59f4762 |
| Source note | uspto-grants-2013_12 |