HuagongsheHuagongshe Chemistry Print Report · For research reference only
17,17-Bis(ethylendioxy)androstan-7-one → HCID 178421203, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 17,17-Bis(ethylendioxy)androstan-7-one | HCID 68950713 | — |
| Reactant | (NE)-N-[(2S,5S,6R,14R,15S)-2,6-dimethyl-18,21,22,25-tetraoxahexacyclo[15.4.4.01,17.02,15.05,14.06,11]pentacosan-12-ylidene]hydroxylamine | HCID 178421204 | — |
| Product | HCID 178421203 | HCID 178421203 | 95% |
Reaction Steps
17,17-Bis(ethylendioxy)-7(E)-hydroxyiminoandrostane was prepared in 95% yield from 3,3:17,17-bis(ethylendioxy)androstane-7-one by the procedure described above for the preparation of 3,3:17,17-bis(ethylendioxy)-6(E)-hydroxyiminoandrostane (Prepn. 20). The combined organic extracts were washed with H2O, dried over Na2SO4 and evaporated to dryness. The crude product was purified by flash chromatography (SiO2, CH2Cl2/MeOH 9/1). 1H-NMR (300 MHz, DMSO-d6, ppm from TMS: δ 10.17 (s, 1H), 3.88-3.70 (m, 8H), 2.89 (m, 1H), 2.23-0.71 (m, 19H), 0.90 (s, 3H), 0.77 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609644B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-b3be9da297414d1a9e27308cd9a4956c |
| Source note | uspto-grants-2013_12 |