HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69133284, compound → 7alpha-Hydroxymethylandrostane-3,17-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69133284 | HCID 69133284 | — |
| Reactant | 17,17-Bis(ethylendioxy)-7alpha-hydroxymethylandrostane | HCID 86635588 | — |
| Product | 7alpha-Hydroxymethylandrostane-3,17-dione | HCID 69007745 | 85% |
Reaction Steps
7α-Hydroxymethylandrostane-3,17-dione (II-bx) was prepared in 85% yield from 3,3:17,17-bis(ethylendioxy)-7α-hydroxymethylandrostane by the procedure described above for the preparation of 6α-cyanoandrostane-3,17-dione (II-ac, Prepn. 3). The combined organic extracts were washed with H2O, dried over Na2SO4 and evaporated to dryness. 1H-NMR (300 MHz, DMSO-d6, ppm from TMS): δ 4.30 (t, 1H), 3.48 (m, 2H), 2.46-0.95 (m, 21H), 1.00 (s, 3H), 0.78 (s, 3H)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609644B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-9f46a6bbacc241f28c4fdf9c76b730c4 |
| Source note | uspto-grants-2013_12 |