Hydroxyamine hydrochloride → HCID 87709516, compound

Participants

Reaction Steps

Following the procedure described in Example 1 and starting from 3α-(3-trifluoroacetamidopropylthio)androstane-6,17-dione (394 mg) and hydroxylamine hydrochloride (64 mg), 3α-(3-trifluoroacetamidopropylthio)-6-(E)-hydroxyiminoandrostane-17-one (203 mg, 50%) was obtained. 1H-NMR (300 MHz, DMSO-d6, ppm from TMS): δ 10.39 (1H, s), 9.42 (1H, t), 3.23 (4H, m), 2.55-0.90 (23H, m), 0.76 (3H, s), 0.67 (3H, s).

Provenance & Evidence