1-Chloro-4-isocyanato-2-(trifluoromethyl) benzene → HCID 59725903, compound

HRID 1912767Notes

Reaction equation

HRID 1912767 reaction equation
[CH3:1][NH:2][C:3]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[N:10]([C:14]1[CH:19]=[CH:18][C:17]([NH2:20])=[CH:16][CH:15]=1)[CH:9]=[CH:8]2)=[O:4].[Cl:21][C:22]1[CH:27]=[CH:26][C:25]([N:28]=[C:29]=[O:30])=[CH:24][C:23]=1[C:31]([F:34])([F:33])[F:32]>>[CH3:1][NH:2][C:3]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[N:10]([C:14]1[CH:19]=[CH:18][C:17]([NH:20][C:29]([NH:28][C:25]3[CH:26]=[CH:27][C:22]([Cl:21])=[C:23]([C:31]([F:33])([F:32])[F:34])[CH:24]=3)=[O:30])=[CH:16][CH:15]=1)[CH:9]=[CH:8]2)=[O:4]

Participants

3

Reactant 2

HCID 27332651-Chloro-4-isocyanato-2-(trifluoromethyl) benzeneHCID 59725981HCID 59725981, compound

Product 1

HCID 59725903HCID 59725903, compound

Procedure

The title compound can be synthesized from 1-(4-aminophenyl)-1H-indole-5-carboxylic acid methylamide and 4-chloro-3-(trifluoromethyl)phenyl isocyanate in the same manner as in Step C in Example 1.

Sources & evidence

ORD record
ord-4f75dc24a5c24841a4c864d48be485df
Source dataset
uspto-grants-2013_12
Patent number
US08609656B2

Reaction notes

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