1-Chloro-4-isocyanato-2-(trifluoromethyl) benzene → HCID 59725932, compound

HRID 1912771Notes

Reaction equation

HRID 1912771 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:16]3[C:11](=[C:12]([O:17][C:18](=[O:20])[CH3:19])[CH:13]=[CH:14][CH:15]=3)[CH:10]=[CH:9]2)=[CH:4][CH:3]=1.[Cl:21][C:22]1[CH:27]=[CH:26][C:25]([N:28]=[C:29]=[O:30])=[CH:24][C:23]=1[C:31]([F:34])([F:33])[F:32]>>[Cl:21][C:22]1[CH:27]=[CH:26][C:25]([NH:28][C:29](=[O:30])[NH:1][C:2]2[CH:3]=[CH:4][C:5]([N:8]3[C:16]4[C:11](=[C:12]([O:17][C:18](=[O:20])[CH3:19])[CH:13]=[CH:14][CH:15]=4)[CH:10]=[CH:9]3)=[CH:6][CH:7]=2)=[CH:24][C:23]=1[C:31]([F:32])([F:33])[F:34]

Participants

3

Reactant 2

HCID 27332651-Chloro-4-isocyanato-2-(trifluoromethyl) benzeneHCID 59725874HCID 59725874, compound

Product 1

HCID 59725932HCID 59725932, compound

Procedure

The title compound can be synthesized from acetic acid 1-(4-aminophenyl)-1H-indol-4-yl ester and 4-chloro-3-(trifluoromethyl)phenyl isocyanate in the same manner as in Step C of Example 1.

Sources & evidence

ORD record
ord-2a3df0d057e44a9db653d770ef73762f
Source dataset
uspto-grants-2013_12
Patent number
US08609656B2

Reaction notes

Loading…