p-Fluoronitrobenzene → HCID 23155169, compound

HRID 1912776Notes

Reaction equation

HRID 1912776 reaction equation
[NH:1]1[C:9]2[CH:8]=[CH:7][CH:6]=[C:5]([OH:10])[C:4]=2[CH:3]=[CH:2]1.[N:11]1([CH2:17][CH2:18]O)[CH2:16][CH2:15][O:14][CH2:13][CH2:12]1.F[C:21]1[CH:26]=[CH:25][C:24]([N+:27]([O-])=O)=[CH:23][CH:22]=1.[Cl:30][C:31]1[CH:36]=[CH:35][C:34]([N:37]=[C:38]=[O:39])=[CH:33][C:32]=1[C:40]([F:43])([F:42])[F:41]>>[Cl:30][C:31]1[CH:36]=[CH:35][C:34]([NH:37][C:38]([NH:27][C:24]2[CH:25]=[CH:26][C:21]([N:1]3[C:9]4[C:4](=[C:5]([O:10][CH2:18][CH2:17][N:11]5[CH2:12][CH2:13][O:14][CH2:15][CH2:16]5)[CH:6]=[CH:7][CH:8]=4)[CH:3]=[CH:2]3)=[CH:22][CH:23]=2)=[O:39])=[CH:33][C:32]=1[C:40]([F:41])([F:42])[F:43]

Participants

5

Reactant 4

HCID 9590p-FluoronitrobenzeneHCID 611632-MorpholinoethanolHCID 754211H-indol-4-olHCID 27332651-Chloro-4-isocyanato-2-(trifluoromethyl) benzene

Product 1

HCID 23155169HCID 23155169, compound

Procedure

The title compound can be synthesized from 1H-indole-4-ol, 2-morpholin-4-ylethanol, 4-fluoronitrobenzene and 4-chloro-3-(trifluoromethyl)phenyl isocyanate in the same manner as in Example 20.

Sources & evidence

ORD record
ord-c3bd6d6936bf4c288ad43078f34aef07
Source dataset
uspto-grants-2013_12
Patent number
US08609656B2

Reaction notes

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