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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1912786Generated: October 31, 2026

2-Methoxyethyl chloroformate → (1-{4-[3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido]phenyl}-1H-benzimidazol-5-yl)carbamic acid 2-methoxyethyl ester

https://huagongshe.com/reaction/1912786

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methoxyethyl chloroformateHCID 69400—
ReactantHCID 23155042HCID 23155042—
Product(1-{4-[3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido]phenyl}-1H-benzimidazol-5-yl)carbamic acid 2-methoxyethyl esterHCID 59725866—

Reaction Steps

The title compound can be synthesized from 1-[4-(5-aminobenzimdazol-1-yl)phenyl]-3-(4-chloro-3-(trifluoro-methyl)phenyl)urea hydrochloride and methoxyethyl chloroformate by the same method as in Example 41.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08609656B2
Source datasetuspto-grants-2013_12
ORD IDord-fc4bac64938244a6a399690792b4fc4c
Source noteuspto-grants-2013_12