p-Fluoronitrobenzene → HCID 23154956, compound

HRID 1912792Notes

Reaction equation

HRID 1912792 reaction equation
[Cl:1][C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[NH:4][CH:5]=[N:6]2.F[C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=O)=[CH:14][CH:13]=1.[Cl:21][C:22]1[CH:27]=[CH:26][C:25]([N:28]=[C:29]=[O:30])=[CH:24][C:23]=1[C:31]([F:34])([F:33])[F:32]>>[Cl:1][C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[N:4]=[CH:5][N:6]2[C:12]1[CH:13]=[CH:14][C:15]([N:18]([OH:20])[C:29]([NH:28][C:25]2[CH:26]=[CH:27][C:22]([Cl:21])=[C:23]([C:31]([F:33])([F:32])[F:34])[CH:24]=2)=[O:30])=[CH:16][CH:17]=1

Participants

4

Reactant 3

HCID 9590p-FluoronitrobenzeneHCID 27332651-Chloro-4-isocyanato-2-(trifluoromethyl) benzeneHCID 53592776-Chloropurine

Product 1

HCID 23154956HCID 23154956, compound

Procedure

The title compound can be synthesized from 6-chloropurine, 4-fluoronitrobenzene and 4-chloro-3-(trifluoromethyl)phenyl isocyanate by using the same techniques as in Example 45.

Sources & evidence

ORD record
ord-55d8451a70394f28a5483516a09389d0
Source dataset
uspto-grants-2013_12
Patent number
US08609656B2

Reaction notes

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