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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1912798Generated: October 31, 2026

Valeryl chloride → n-(1-{4-[3-(4-Chloro-3-(trifluoromethyl)phenyl)-3-hydroxyureido]phenyl}-1h-indol-5-yl)pentanamide

https://huagongshe.com/reaction/1912798

Reaction equation

Participants

RoleNameHCIDCharge
ReactantValeryl chlorideHCID 61186—
ReactantHCID 23155046HCID 23155046—
Productn-(1-{4-[3-(4-Chloro-3-(trifluoromethyl)phenyl)-3-hydroxyureido]phenyl}-1h-indol-5-yl)pentanamideHCID 23155261—

Reaction Steps

The title compound can be synthesized from 1-[4-(5-aminoindol-1-yl)phenyl]-3-(4-chloro-3-(trifluoromethyl)phenyl)-3-hydroxyurea hydrochloride and n-valeroyl chloride by using the same techniques as in Example 41.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08609656B2
Source datasetuspto-grants-2013_12
ORD IDord-0712cc5a4a5440b6b21728d2058ee435
Source noteuspto-grants-2013_12