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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1912802Generated: November 1, 2026

2-Methoxyethyl chloroformate → (1-{4-[3-(4-Chloro-3-(trifluoromethyl)phenyl)-3-hydroxyureido]phenyl}-1H-indol-5-yl)carbamic acid 2-methoxyethyl ester

https://huagongshe.com/reaction/1912802

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methoxyethyl chloroformateHCID 69400—
ReactantHCID 23155046HCID 23155046—
Product(1-{4-[3-(4-Chloro-3-(trifluoromethyl)phenyl)-3-hydroxyureido]phenyl}-1H-indol-5-yl)carbamic acid 2-methoxyethyl esterHCID 59725897—

Reaction Steps

The title compound can be synthesized from 1-[4-(5-aminoindol-1-yl)phenyl]-3-(4-chloro-3-(trifluoromethyl)phenyl)-3-hydroxyurea hydrochloride and 2-methoxyethyl chloroformate by using the same techniques as in Example 41.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08609656B2
Source datasetuspto-grants-2013_12
ORD IDord-6e74b421aeb641599951625a672601a0
Source noteuspto-grants-2013_12