1-Chloro-4-isocyanato-2-(trifluoromethyl) benzene → HCID 59725869, compound

HRID 1912809Notes

Reaction equation

HRID 1912809 reaction equation
[CH3:1][N:2]([CH3:26])[CH2:3][CH2:4][NH:5][C:6]([C:8]1[C:13]2[N:14]=[CH:15][N:16]([C:17]3[CH:22]=[CH:21][C:20]([N+:23]([O-])=O)=[CH:19][CH:18]=3)[C:12]=2[CH:11]=[CH:10][N:9]=1)=[O:7].[Cl:27][C:28]1[CH:33]=[CH:32][C:31]([N:34]=[C:35]=[O:36])=[CH:30][C:29]=1[C:37]([F:40])([F:39])[F:38]>>[CH3:1][N:2]([CH3:26])[CH2:3][CH2:4][NH:5][C:6]([C:8]1[C:13]2[N:14]=[CH:15][N:16]([C:17]3[CH:22]=[CH:21][C:20]([NH:23][C:35]([NH:34][C:31]4[CH:32]=[CH:33][C:28]([Cl:27])=[C:29]([C:37]([F:39])([F:38])[F:40])[CH:30]=4)=[O:36])=[CH:19][CH:18]=3)[C:12]=2[CH:11]=[CH:10][N:9]=1)=[O:7]

Participants

3

Reactant 2

HCID 27332651-Chloro-4-isocyanato-2-(trifluoromethyl) benzeneHCID 59725960HCID 59725960, compound

Product 1

HCID 59725869HCID 59725869, compound

Procedure

The title compound can be synthesized from 1-(4-nitrophenyl)-1H-imidazo[4,5-c]pyridine-4-carboxylic acid (2-(dimethylamino)ethyl)amide and 4-chloro-3-(trifluoromethyl)phenyl isocyanate in the same manner as in Steps B and C of Example 1.

Sources & evidence

ORD record
ord-a854d12d7e75477c8be2cad5b6a65090
Source dataset
uspto-grants-2013_12
Patent number
US08609656B2

Reaction notes

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