HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethyl chloroformate → (9-{4-[3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido]-phenyl}-9H-purin-6-yl)carbamic acid 2-methoxyethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethyl chloroformate | HCID 69400 | — |
| Reactant | 1-[4-(6-Aminopurin-9-yl)phenyl]-3-(4-chloro-3-(trifluoromethyl)phenyl)urea hydrochloride | HCID 23155120 | — |
| Product | (9-{4-[3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido]-phenyl}-9H-purin-6-yl)carbamic acid 2-methoxyethyl ester | HCID 59725931 | — |
Reaction Steps
The title compound can be synthesized from 1-[4-(6-aminopurin-9-yl)phenyl]-3-(4-chloro-3-(trifluoromethyl)phenyl)urea hydrochloride and 2-methoxyethyl chloroformate by using the same method as in Example 107.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609656B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-d1b75a245e2d4d1c9eee50fa7c4803aa |
| Source note | uspto-grants-2013_12 |