反应详情

温度

120 °C

In 20 mL of a 40% methylamine methanol solution and 20 mL of ethanol, 12.5 g (79 mmol) of 6-chloropurin was dissolved and the solution was sealed in a tube and stirred in the tube at 120° C. for four hours. The reaction solution was concentrated, and then triturated with water and collected on a filter, washed with water, and then vacuum dried to obtain 10.78 g (90%) of methyl-(9H-purin-6-yl)amine as a white solid.

1. customthe solution was sealed in a tube
2. concentrationThe reaction solution was concentrated
3. customtriturated with water
4. customcollected on a filter
5. washwashed with water
6. customvacuum dried