alpha,alpha,alpha-Trifluoro-3,5-dinitrotoluene → 5-(Trifluoromethyl)benzene-1,3-diamine

Participants

Reaction Steps

In a mixed solvent of 10 mL of ethyl acetate and 1 mL of methanol, 500 mg (2.12 mmol) of 3,5-dinitrobenzotrifluoride was dissolved, and 20 mg of 10% palladium carbon was added thereto, and the mixture solution was stirred at room temperature for 20 hours in a hydrogen atmosphere at normal pressures. The catalyst was removed by filtration, and the filtrate was concentrated and dried to obtain 380 mg (100%) of a brown oily target product.

Provenance & Evidence