HuagongsheHuagongshe Chemistry Print Report · For research reference only
trans-2-[4-(Trifluoromethyl)phenyl]vinylboronic acid → HCID 68752913, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | trans-2-[4-(Trifluoromethyl)phenyl]vinylboronic acid | HCID 6153620 | — |
| Reactant | 3,3-dimethyl-N-[3-(pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-2-yl]butanamide | HCID 68751160 | — |
| Product | HCID 68752913 | HCID 68752913 | — |
Reaction Steps
Trans-2-[4-(trifluoromethyl)phenyl]vinylboronic acid and the product from Example 110B were processed using the method analogous to that described in Example 110C to provide the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 10.27-10.28 (bs, 1H), 9.11 (dd, J=6.9, 1.7 Hz, 1H), 8.69 (dd, J=4.1, 1.7 Hz, 1H), 7.63-7.73 (m, 5H), 7.34 (d, J=16.5 Hz, 1H), 7.15 (dd, J=6.9, 4.1 Hz, 1H), 2.35 (s, 2H), 1.09 (s, 9H); MS (ESI) m/z 403 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609669B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-eb41a81df5444db492c8637bc2d71f16 |
| Source note | uspto-grants-2013_12 |