HuagongsheHuagongshe Chemistry Print Report · For research reference only
trans-2-[4-(Trifluoromethyl)phenyl]vinylboronic acid → HCID 68751801, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | trans-2-[4-(Trifluoromethyl)phenyl]vinylboronic acid | HCID 6153620 | — |
| Reactant | N-(3-bromopyrazolo[1,5-a]pyrimidin-2-yl)-3-cyclopentylpropanamide | HCID 68752925 | — |
| Product | HCID 68751801 | HCID 68751801 | — |
Reaction Steps
Trans-2-[4-(trifluoromethyl)phenyl]vinylboronic acid and the product from Example 153A were processed using the method analogous to that described in Example 110C to provide the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 10.32-10.34 (bs, 1H), 9.10 (dd, J=6.9, 1.7 Hz, 1H), 8.69 (dd, J=4.1, 1.7 Hz, 1H), 7.70 (s, 4H), 7.64 (d, J=16.3 Hz, 1H), 7.34 (d, J=16.2 Hz, 1H), 7.14 (dd, J=6.9, 4.1 Hz, 1H), 2.49 (t, J=7.9 Hz, 2H), 1.76-1.86 (m, 3H), 1.45-1.70 (m, 6H), 1.07-1.18 (m, 2H); MS (ESI) m/z 429 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609669B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-b5d400ebd35e4083abc06fbf098ac6f0 |
| Source note | uspto-grants-2013_12 |