反应详情

The product from Example 140A and 3,3-dimethyl-1-butenylboronic acid were processed using the method analogous to that described in Example 110C to provide the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 10.32-10.43 (bs, 1H), 8.99 (dd, J=7.0, 1.7 Hz, 1H), 8.56 (dd, J=4.1, 1.7 Hz, 1H), 7.37-7.43 (m, 2H), 7.13-7.21 (m, 2H), 7.04 (dd, J=7.0, 4.1 Hz, 1H), 6.63 (d, J=16.3 Hz, 1H), 6.08 (d, J=16.5 Hz, 1H), 3.70 (s, 2H), 1.01 (s, 9H); MS (APCI) m/z 353 (M+H)+.