HuagongsheHuagongshe Chemistry Print Report · For research reference only
((1E)-prop-1-en-1-yl)boronic acid → HCID 68752455, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ((1E)-prop-1-en-1-yl)boronic acid | HCID 6157276 | — |
| Reactant | 3,3-dimethyl-N-[3-(pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-2-yl]butanamide | HCID 68751160 | — |
| Product | HCID 68752455 | HCID 68752455 | — |
Reaction Steps
The product from Example 110B and trans-1-propen-1-ylboronic acid were processed using the method analogous to that described in Example 110C to provide the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 9.99-10.02 (bs, 1H), 8.99 (dd, J=6.9, 1.7 Hz, 1H), 8.54 (dd, J=4.1, 1.7 Hz, 1H), 7.02 (dd, J=6.9, 4.1 Hz, 1H), 6.63 (dq, J=15.8, 6.6 Hz, 1H), 6.31 (dd, J=15.9, 2.0 Hz, 1H), 2.26 (s, 2H), 1.85 (dd, J=6.6, 1.7 Hz, 3H), 1.06 (s, 9H); MS (ESI) m/z 273 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609669B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-049ccdb3aff9430b8f441a01413911a3 |
| Source note | uspto-grants-2013_12 |