HuagongsheHuagongshe Chemistry Print Report · For research reference only
(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid → HCID 68750749, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid | HCID 118342 | — |
| Reactant | 3-Tert-butylpyrazolo[1,5-a]pyrimidin-2-amine | HCID 68755471 | — |
| Product | HCID 68750749 | HCID 68750749 | — |
Reaction Steps
The product from Example 105B and 2-(4-(trifluoromethyl)phenyl)acetic acid were processed using the method analogous to that described in Example 137 to afford the title compound. 1H NMR (400 MHz, DMSO-d6/Deuterium Oxide) δ ppm 8.87 (dd, J=6.9, 1.0 Hz, 1H), 8.49 (dd, J=4.0, 1.8 Hz, 1H), 7.67-7.75 (m, 2H), 7.51-7.64 (m, 2H), 7.01 (dd, J=7.0, 4.0 Hz, 1H), 3.75-3.80 (bs, 2H), 1.39 (s, 9H); MS (ESI) m/z 377 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609669B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-2f35ac31497743dbbcc5ee86d36a8cba |
| Source note | uspto-grants-2013_12 |