HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichlorophenylacetic acid → N-(3-tert-butylpyrazolo[1,5-a]pyrimidin-2-yl)-2-(2,6-dichlorophenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichlorophenylacetic acid | HCID 81058 | — |
| Reactant | 3-Tert-butylpyrazolo[1,5-a]pyrimidin-2-amine | HCID 68755471 | — |
| Product | N-(3-tert-butylpyrazolo[1,5-a]pyrimidin-2-yl)-2-(2,6-dichlorophenyl)acetamide | HCID 68749167 | — |
Reaction Steps
The product from Example 105B and 2-(2,6-dichlorophenyl)acetic acid were processed using the method analogous to that described in Example 137 to afford the title compound. 1H NMR (400 MHz, DMSO-d6/Deuterium Oxide) δ ppm 8.89 (d, J=6.4 Hz, 1H), 8.49 (d, J=2.0 Hz, 1H), 7.46-7.52 (m, 2H), 7.35 (dd, J=7.9 Hz, 1H), 7.01 (dd, J=6.6, 3.9 Hz, 1H), 4.05-4.09 (bs, 2H), 1.48 (s, 9H); MS (ESI) m/z 377, 379 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609669B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-210babf91efc45ce81481880b9f9da0e |
| Source note | uspto-grants-2013_12 |