HCID 67370591, compound → HCID 178511691, compound

HRID 1913119Notes

Reaction equation

HRID 1913119 reaction equation
Cl.F[C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[N:8][CH:7]=[CH:6]2.[NH2:13][C@@H:14]1[CH2:19][CH2:18][C@H:17]([OH:20])[CH2:16][CH2:15]1>>[CH:9]1[C:10]2[C:5](=[CH:4][C:3]([O:20][C@@H:17]3[CH2:18][CH2:19][C@H:14]([NH2:13])[CH2:15][CH2:16]3)=[CH:12][CH:11]=2)[CH:6]=[CH:7][N:8]=1

Participants

3

Reactant 2

HCID 67370591HCID 67370591, compoundHCID 178511714HCID 178511714, compound

Product 1

HCID 178511691HCID 178511691, compound

Procedure

Starting from 6-fluoro-isoquinoline hydrochloride and cis-4-amino-cyclohexanol the title compound was prepared following the protocol described for compound (15). Rt=0.64 min (Method B). Detected mass: 243.2 (M+H+).

Sources & evidence

ORD record
ord-a992c50051284545902b2c8882b0deb8
Source dataset
uspto-grants-2013_12
Patent number
US08609691B2

Reaction notes

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