(2R)-2,3-Dihydroxypropanoic acid → HCID 135998729, compound

HRID 1913265Notes

Reaction equation

HRID 1913265 reaction equation
[OH:1][C@H:2]([CH3:35])[C:3]([N:5]1[CH2:10][CH2:9][CH:8]([C:11]2[C:16]3[CH:17]=[CH:18][NH:19][C:15]=3[N:14]3[N:20]=[CH:21][C:22]([C:23]4[CH:24]=[N:25][C:26]([C:29]5[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=5)=[CH:27][CH:28]=4)=[C:13]3[N:12]=2)[CH2:7][CH2:6]1)=[O:4].[OH:36][C@H](CO)C(O)=O>>[OH:1][C@H:2]([CH2:35][OH:36])[C:3]([N:5]1[CH2:6][CH2:7][CH:8]([C:11]2[C:16]3[CH:17]=[CH:18][NH:19][C:15]=3[N:14]3[N:20]=[CH:21][C:22]([C:23]4[CH:24]=[N:25][C:26]([C:29]5[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=5)=[CH:27][CH:28]=4)=[C:13]3[N:12]=2)[CH2:9][CH2:10]1)=[O:4]

Participants

3

Reactant 2

HCID 439194(2R)-2,3-Dihydroxypropanoic acidHCID 135998730HCID 135998730, compound

Product 1

HCID 135998729HCID 135998729, compound

Procedure

The title compound was prepared in a similar way to compound 25, except that (R)-2,3-dihydroxypropanoic acid was used in place of D-lactic acid in Step C. LC/MS (10 min method) RT: 2.63 min, [M+]=482.21, [M+H]=483.21

Workup

  1. customLC/MS (10 min method) RT: 2.63 min, [M+]=482.21, [M+H]=483.21

Sources & evidence

ORD record
ord-ec8f8790b32149c8aeb16510bb3b981d
Source dataset
uspto-grants-2013_12
Patent number
US08609675B2

Reaction notes

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