HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfanilamide → 4-[2-(2-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfanilamide | HCID 5333 | — |
| Reactant | Methyl vinyl ketone | HCID 6570 | — |
| Reactant | o-Fluorobenzaldehyde | HCID 67970 | — |
| Product | 4-[2-(2-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonamide | HCID 68484455 | — |
Reaction Steps
2-Fluorobenzaldehyde and but-3-en-2-one were treated according to the procedure outlined in General Procedure C followed by subjecting the resulting product to conditions outlined in General Procedure D along with p-aminosulfonyl phenylamine to obtain the titled compound. 1H NMR (CDCl3) δ ppm 2.18 (3H), 4.71 (2H), 6.13 (1H), 6.34 (1H), 7.05-7.90 (8H); MS (ESI) m/z 331 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609713B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-72ba0acdcc5a4fd2befad330f2d163fa |
| Source note | uspto-grants-2013_12 |