Sulfuryl chloride → [(Chlorocarbonyl)oxy]methyl 2-methylpropanoate

The compound (400 mg) obtained in Step 2 of this Example was cooled to −30° C. Sulfuryl chloride (159 μL) was added thereto, and the mixture was stirred at the same temperature for 20 minutes. The mixture was in turn stirred for 20 minutes in an ice bath and further at room temperature for 1 hour. The solvent was distilled off under reduced pressure, and the residue was dried to obtain a crude product of the title compound.

1. customwas cooled to −30° C
2. stirringstirred for 20 minutes in an ice bath and further at room temperature for 1 hour
3. distillationThe solvent was distilled off under reduced pressure
4. customthe residue was dried

ORD record

ord-c58152f509424c4793a0f1ef193ef4f6

Source dataset

uspto-grants-2013_12

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US08609710B2