HCID 178461172, compound → HCID 178461173, compound

Participants

Reaction Steps

The compound (830 mg) obtained in Step 2 of this Example was dissolved in ethanol (25 mL). To the solution, 10% palladium-carbon catalyst (hydrated, 207 mg) was added, and the mixture was stirred for 13 hours under a hydrogen atmosphere. The catalyst was filtered off, and the solvent in the filtrate was distilled off under reduced pressure. The obtained residue was purified by silica gel column chromatography (eluting solvent: hexane/ethyl acetate=1/1-ethyl acetate) to obtain the title compound (788 mg).

Provenance & Evidence