HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1913568Generated: November 2, 2026
Triethyl phosphite → tert-Butyl 2-(diethoxyphosphoryl)propanoate
https://huagongshe.com/reaction/1913568
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Reactant | tert-Butyl 2-bromopropanoate | HCID 545327 | — |
| Product | tert-Butyl 2-(diethoxyphosphoryl)propanoate | HCID 11644679 | 108.1% |
Reaction Steps
2-Bromo-propanoic acid tert-butyl ester (17.4 g, 83 mmol) and triethyl phosphite (14.5 g, 87 mmol) were mixed, and the mixture was stirred at 110° C. overnight. The reaction mixture was dried under reduced pressure to give the title compound (23.9 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08609715B2 |
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| Source dataset | uspto-grants-2013_12 |
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| ORD ID | ord-02939b96b51c4625a15fc0ba2a5ca45c |
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| Source note | uspto-grants-2013_12 |
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