HCID 77934570, compound → HCID 70869380, compound

HRID 1913583Notes

Reaction equation

[C:1]([O:5][C:6]([C:8]([CH3:24])=[CH:9][C:10]1[S:14][C:13]([CH2:15][O:16][Si:17]([C:20]([CH3:23])([CH3:22])[CH3:21])([CH3:19])[CH3:18])=[N:12][CH:11]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]>C(O)C.[Pd]>[C:1]([O:5][C:6]([CH:8]([CH3:24])[CH2:9][C:10]1[S:14][C:13]([CH2:15][O:16][Si:17]([C:20]([CH3:23])([CH3:22])[CH3:21])([CH3:18])[CH3:19])=[N:12][CH:11]=1)=[O:7])([CH3:2])([CH3:4])[CH3:3]

Participants

Conditions

Temperature: 50 °C

Procedure

The compound (0.5 g, 1.4 mmol) obtained in step 3 was dissolved in ethanol (20 ml), palladium/carbon (0.1 g) was added, and the mixture was stirred at 50° C. for 20 hours under a hydrogen atmosphere (55 psi). The reaction mixture was filtered, and the solvent was evaporated under reduced pressure to give the title compound (0.3 g).

Workup

filtrationThe reaction mixture was filtered
customthe solvent was evaporated under reduced pressure

Sources & evidence

ORD record: ord-cb68ac1670c640c4bf9d695ca0ccbfbe
Source dataset: uspto-grants-2013_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08609715B2

Reaction notes

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