Potassium Carbonate → HCID 59180536, compound

Participants

Reaction Steps

A solution of 200 mg (0.486 mmol) of methyl 4-[(3E)-2-[2-(4-cyanophenyl)ethyl]-4-(2-hydroxyphenyl)but-3-en-1-yl]benzoate in 5 ml of acetonitrile is mixed with 145 mg (0.73 mmol) of (3-bromopropyl)benzene and 100.76 mg (0.73 mmol) of potassium carbonate and then stirred under reflux for 12 h. After cooling, the potassium carbonate is filtered off and the filtrate is evaporated. 278 mg (0.45 mmol, 93% of theory, content 86%) of the title compound are obtained.

Provenance & Evidence