Potassium Carbonate → HCID 59180522, compound

Participants

Reaction Steps

A solution of 200 mg (0.49 mmol) of methyl 4-[(3E)-2-[2-(4-cyanophenyl)ethyl]-4-(2-hydroxyphenyl)but-3-en-1-yl]benzoate in 25 ml of acetonitrile is mixed with 176 mg (0.73 mmol) of (6-bromohexyl)benzene and 101 mg (0.73 mmol) of potassium carbonate and then stirred under reflux for 12 h. After cooling, the potassium carbonate is filtered off and the filtrate is evaporated. 364 mg (0.48 mmol, 98% of theory, purity 76%) of a yellowish oil are obtained.

Provenance & Evidence