HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-1-(tetrahydrofuran-2-yl)methyl methanesulfonate → N-((S)-6-Bromo-1,2,3,4-tetrahydronaphthalen-2-yl)-4-[(S)-1-(tetrahydrofuran-2-yl)methoxy]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-1-(tetrahydrofuran-2-yl)methyl methanesulfonate | HCID 18649743 | — |
| Reactant | N-((S)-6-bromo-1,2,3,4-tetrahydronaphthalen-2-yl)-4-hydroxybenzamide | HCID 66663475 | — |
| Product | N-((S)-6-Bromo-1,2,3,4-tetrahydronaphthalen-2-yl)-4-[(S)-1-(tetrahydrofuran-2-yl)methoxy]benzamide | HCID 67545579 | — |
Reaction Steps
According to method F, N-((S)-6-bromo-1,2,3,4-tetrahydronaphthalen-2-yl)-4-hydroxybenzamide was reacted with methanesulfonic acid (S)-1-(tetrahydrofuran-2-yl)methyl ester. The product was thus obtained with the molecular weight of 430.35 (C22H24BrNO3); MS (ESI): 430 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609731B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-a72ba1a0133c45ac89e7e287db4989c0 |
| Source note | uspto-grants-2013_12 |