HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1913829Generated: October 25, 2026
6-[(S)-1-(tetrahydrofuran-2-yl)methoxy]isochromen-1-one → HCID 59506001, compound
https://huagongshe.com/reaction/1913829
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 6-[(S)-1-(tetrahydrofuran-2-yl)methoxy]isochromen-1-one | HCID 66879690 | — |
| Reactant | HCID 67545539 | HCID 67545539 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 59506001 | HCID 59506001 | — |
Reaction Steps
A mixture of 6-[(S)-1-(tetrahydrofuran-2-yl)methoxy]isochromen-1-one (50 mg), NMP (0.2 ml) and (S)-6-(4-methoxypiperidin-1-ylmethyl)-1,2,3,4-tetrahydro-naphthalen-2-ylamine (55 mg) was heated to 220° C. in a microwave reactor for 3×30 minutes. The cooled reaction mixture was purified by preparative HPLC. The product was thus obtained with the molecular weight of 502.66 (C31H38N2O4); MS (ESI): 503 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08609731B2 |
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| Source dataset | uspto-grants-2013_12 |
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| ORD ID | ord-8e3e6c20e18c4d239e187ca699b747c9 |
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| Source note | uspto-grants-2013_12 |
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