(2S)-6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine → HCID 67545250, compound

HRID 1913838Notes

Reaction equation

HRID 1913838 reaction equation
[O:1]1[CH2:5][CH2:4][CH2:3][C@H:2]1[CH2:6][O:7][C:8]1[CH:9]=[C:10]2[C:15](=[CH:16][CH:17]=1)[C:14](=[O:18])O[CH2:12][CH2:11]2.[Br:19][C:20]1[CH:21]=[C:22]2[C:27](=[CH:28][CH:29]=1)[CH2:26][C@@H:25]([NH2:30])[CH2:24][CH2:23]2>>[Br:19][C:20]1[CH:21]=[C:22]2[C:27](=[CH:28][CH:29]=1)[CH2:26][C@@H:25]([N:30]1[CH2:12][CH2:11][C:10]3[C:15](=[CH:16][CH:17]=[C:8]([O:7][CH2:6][C@@H:2]4[CH2:3][CH2:4][CH2:5][O:1]4)[CH:9]=3)[C:14]1=[O:18])[CH2:24][CH2:23]2

Participants

3

Reactant 2

HCID 22831536(2S)-6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amineHCID 666799246-[(S)-1-(Tetrahydrofuran-2-yl)methoxy]isochroman-1-one

Product 1

HCID 67545250HCID 67545250, compound

Procedure

According to method O, 6-[(S)-1-(tetrahydrofuran-2-yl)methoxy]isochroman-1-one was reacted with (S)-6-bromo-1,2,3,4-tetrahydronaphthalen-2-ylamine (J. Org. Chem. 1995, 60, 4324). The product was thus obtained with the molecular weight of 456.38 (C24H26BrNO3); MS (ESI): 456 (M+H+).

Workup

  1. customThe product was thus obtained with the molecular weight of 456.38 (C24H26BrNO3)

Sources & evidence

ORD record
ord-ee87cbf5932743c6ab19b48da3c54294
Source dataset
uspto-grants-2013_12
Patent number
US08609731B2

Reaction notes

Loading…