4-(4-Chloro-phenyl)-2-(4-iodo-imidazol-1-yl)-6-methyl-pyrimidine → N-tert-Butyl-5-{1-[6-(4-chloro-phenyl)-4-methyl-pyrimidin-2-yl]-1H-imidazol-4-yl}-thiophene-2-sulfonamide

HRID 191396Notes

Reaction equation

HRID 191396 reaction equation
[C:21]([CH3:22])([CH3:23])([CH3:24])[NH:25][S:26](=[O:27])(=[O:28])[c:29]1[s:30][c:31]([B:34]2[O:35][C:36]([CH3:37])([CH3:38])[C:39]([CH3:40])([CH3:41])[O:42]2)[cH:32][cH:33]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10](-[n:15]3[cH:16][n:17][c:18]([I:20])[cH:19]3)[n:11][c:12]([CH3:14])[cH:13]2)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10](-[n:15]3[cH:16][n:17][c:18](-[c:31]4[s:30][c:29]([S:26]([NH:25][C:21]([CH3:22])([CH3:23])[CH3:24])(=[O:27])=[O:28])[cH:33][cH:32]4)[cH:19]3)[n:11][c:12]([CH3:14])[cH:13]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 574687834-(4-Chloro-phenyl)-2-(4-iodo-imidazol-1-yl)-6-methyl-pyrimidineHCID 57468817N-tert-butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-sulfonamide

Product 1

HCID 57468939N-tert-Butyl-5-{1-[6-(4-chloro-phenyl)-4-methyl-pyrimidin-2-yl]-1H-imidazol-4-yl}-thiophene-2-sulfonamide

Sources & evidence

ORD record
ord-8d7bf4bd0b904bb29ddef126c9c3ea63
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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