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HRID1914094

反应详情

EQUATION

反应方程式

HRID 1914094 的结构方程式

REACTANTS

反应物

2
结构：Cc1cccc(S(=O)(=O)Cl)c1
HCID2734595

3-methylbenzenesulfonyl Chloride

C7H7ClO2S

结构：COc1cc(C2=NN(C3CCNCC3)C(=O)C2(C)C)cc2c1OC(C)(C)C2
HCID67363308

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(C2=NN(C3CCN(S(=O)(=O)c4cccc(C)c4)CC3)C(=O)C2(C)C)cc2c1OC(C)(C)C2
HCID46204004

未命名化合物

PROCEDURE

实验过程

The title compound is prepared analogously as described for GP1 using 5-(7-methoxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-5-yl)-4,4-dimethyl-2-(piperidin-4-yl)-2,4-dihydro-3H-pyrazol-3-one (compound B12) and 3-methylbenzenesulfonyl chloride as starting compounds. The crude product is purified by chromatography (amino phase silica gel and DCM) and crystallization of the product containing fractions from DCM and diethyl ether to yield the title compound.

WORKUP

后处理

  1. customThe title compound is prepared analogously
  2. customThe crude product is purified by chromatography (amino phase silica gel and DCM) and crystallization of the product
  3. additioncontaining fractions from DCM and diethyl ether