HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 5-(Benzyloxy)-2-methylbenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 5-(Benzyloxy)-2-methylbenzoic acid | HCID 59760047 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-(Benzyloxy)-2-methylbenzoyl chloride | HCID 86657436 | — |
Reaction Steps
To a mixture of 3.3 g 5-(benzyloxy)-2-methylbenzoic acid (compound F1) in 80 ml DCM are added 1.4 ml of oxaloylchloride, and the reaction is stirred at RT over night under a blanket of nitrogen. The solvent is removed under reduced pressure yielding the title compound, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609848B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-17d9113c90cb4d16abc4ae1940817b67 |
| Source note | uspto-grants-2013_12 |