HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Fluoro-2-methylphenyl)boronic acid → 3-{4-[1-(4'-Fluoro-2'-methyl-biphenyl-4-yloxy)-heptyl]-benzoylamino}-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Fluoro-2-methylphenyl)boronic acid | HCID 2734665 | — |
| Reactant | 3-{4-[1-(4-Bromo-phenoxy)-heptyl]-benzoylamino}-propionic acid methyl ester | HCID 67153387 | — |
| Product | 3-{4-[1-(4'-Fluoro-2'-methyl-biphenyl-4-yloxy)-heptyl]-benzoylamino}-propionic acid | HCID 58995090 | — |
Reaction Steps
This compound is made in a substantially similar manner as Example 117 using isomer 1 of 3-{4-[1-(4-bromo-phenoxy)-heptyl]-benzoylamino}-propionic acid methyl ester and 4-fluoro-2-methyl-phenylboronic acid as starting materials in step D. MS (ES): 492.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609892B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-95203d881a8041479c06fa2a782917fa |
| Source note | uspto-grants-2013_12 |