4-Isopropylphenylboronic acid → HCID 59518061, compound

HRID 1914376Notes

Reaction equation

HRID 1914376 reaction equation
C[O:2][C:3](=[O:31])[CH2:4][CH2:5][NH:6][C:7](=[O:30])[C:8]1[CH:13]=[CH:12][C:11]([CH:14]([O:22][C:23]2[CH:28]=[CH:27][C:26](Br)=[CH:25][CH:24]=2)[CH2:15][CH2:16][CH2:17][C:18]([F:21])([F:20])[F:19])=[CH:10][CH:9]=1.[CH:32]([C:35]1[CH:40]=[CH:39][C:38](B(O)O)=[CH:37][CH:36]=1)([CH3:34])[CH3:33]>>[F:19][C:18]([F:21])([F:20])[CH2:17][CH2:16][CH2:15][CH:14]([C:11]1[CH:10]=[CH:9][C:8]([C:7]([NH:6][CH2:5][CH2:4][C:3]([OH:2])=[O:31])=[O:30])=[CH:13][CH:12]=1)[O:22][C:23]1[CH:24]=[CH:25][C:26]([C:38]2[CH:39]=[CH:40][C:35]([CH:32]([CH3:34])[CH3:33])=[CH:36][CH:37]=2)=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 27734804-Isopropylphenylboronic acidHCID 67153380HCID 67153380, compound

Product 1

HCID 59518061HCID 59518061, compound

Procedure

The title compound is prepared in a manner substantially similar to Example 128 starting from 3-{4-[1-(4-bromo-phenoxy)-5,5,5-trifluoro-pentyl]-benzoylamino}-propionic acid methyl ester and 4-isopropyl phenyl boronic acid. MS: 526.2 [M−H]−.

Sources & evidence

ORD record
ord-28124e955e754a3aa45157778d449ff9
Source dataset
uspto-grants-2013_12
Patent number
US08609892B2

Reaction notes

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