Dimethylformamide → HCID 58050547, compound

Participants

Reaction Conditions

Reaction Steps

A mixed solution of 59 g of 1-bromopyrene, 40 g of p-chlorophenylboronic acid, 108 g of tripotassium phosphate, g of tetrabutylammonium bromide, 1.15 g of palladium acetate and 1,250 ml of dimethylformamide was heated and stirred under a nitrogen gas stream at 130° C. for 3 hours. The solution was cooled to room temperature and 1,000 ml of water was poured into the solution, followed by filtration. The resulting solid was washed with 200 ml of methanol, dissolved in 1,000 ml of dichloromethane, dried over magnesium sulfate, filtered through Celite and then evaporated. The resulting solid was washed with 200 ml of methanol and then vacuum-dried to obtain 58.2 g of 1-(4-chlorophenyl)pyrene.

Provenance & Evidence