反应详情

A mixed solution of 4.1 g of pyrene, 2 g of t-butylchloride and 33 ml of dichloromethane was cooled to 0° C. under a nitrogen gas stream and then 2.7 g of aluminum chloride was added. This mixed solution was stirred at room temperature for 3 hours and 30 ml of water was poured into the solution, followed by extraction with 30 ml of dichloromethane. The organic layer was washed twice with 20 ml of water, dried over magnesium sulfate and then evaporated. The concentrate was purified by silica gel column chromatography and then vacuum-dried to obtain 3 g (content: 65%) of 2-t-butylpyrene.

1. extractionfollowed by extraction with 30 ml of dichloromethane
2. washThe organic layer was washed twice with 20 ml of water
3. dry with materialdried over magnesium sulfate
4. customevaporated
5. customThe concentrate was purified by silica gel column chromatography
6. customvacuum-dried