Disodium oxoglurate → HCID 131731097, compound

Participants

Reaction Steps

2-ketoglutaric acid disodium salt (0.4 g, 2.1 mmol) was dissolved in 6 mL of water. Triphenylsulfonium bromide (1.4 g, 4.1 mmol) was dissolved in 12 mL dichloromethane. The salt solution was added dropwise to the triphenylsulfonium bromide solution and the mixture was stirred overnight at room temperature. The reaction mixture was evaporated to dryness (or on oil stage) on a rotary evaporator. The product obtained from evaporation was washed with ethyl ether and dissolved using an excess amount of dichloromethane and filtered. After the evaporation of dichloromethane, the pure compound was obtained as a white solid.

Provenance & Evidence