5-Chlorosalicylic Acid → HCID 44241054, compound

HRID 1914482Notes

Reaction equation

HRID 1914482 reaction equation
[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[CH:12]([C:14]1[CH:15]=[C:16]([CH:18]=[CH:19][CH:20]=1)[NH2:17])=[CH2:13]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:17][C:16]1[CH:18]=[CH:19][CH:20]=[C:14]([CH:12]=[CH2:13])[CH:15]=1)=[O:9]

Participants

3

Reactant 2

HCID 94475-Chlorosalicylic AcidHCID 42600413-Aminostyrene

Product 1

HCID 44241054HCID 44241054, compound

Procedure

This material was prepared according to the method of Example 1 using 5-chlorosalicylic acid and 3-vinylaniline, with reagents and solvents employed in similar molar ratios. 1HNMR (500 MHz, DMSO-d6): δ 5.32 (m, 1H, C═CH2 cis), 5.83 (m, 1H, C═CH2trans), 6.75 (m, 1H, ArCH═CH2), 7.02 (m, 1H, H3), 7.28 (m, 1H, H6′), 7.37 (m, 1H, H5′), 7.49 (m, 1H, H4), 7.62 (m, 1H, H4′), 7.80 (m, 1H, H2′), 7.90 (m, 1H, H6).

Workup

  1. customThis material was prepared

Sources & evidence

ORD record
ord-7e229343008a41d391af7383247c1668
Source dataset
uspto-grants-2013_12
Patent number
US08614205B2

Reaction notes

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