Sodium Nitrate → HCID 178524577, compound

HRID 1914596Notes

Reaction equation

HRID 1914596 reaction equation
[OH:1][C:2]1[N:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[N+:11]([O-])([O-:13])=[O:12].[Na+]>S(=O)(=O)(O)O>[OH:1][C:2]1[N:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5]

Participants

4

Reactant 2

HCID 24268Sodium NitrateHCID 178418543HCID 178418543, compound

Product 1

HCID 178524577HCID 178524577, compoundYield 45%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

To 2-hydroxy-nicotinic acid (3.6 mmol) in sulfuric acid (30% free SO3, 2 ml) was added sodium nitrate (7.2 mmol) portionwise over 20 min. The solution was allowed to stir for 20 h at room temperature. The solution was then poured onto ice-water and the precipitate that formed was filtered off, washed with water and dried in a vacuum oven to afford a pale yellow solid (45%).

Workup

  1. additionThe solution was then poured onto ice-water
  2. customthe precipitate that formed
  3. filtrationwas filtered off
  4. washwashed with water
  5. customdried in a vacuum oven

Sources & evidence

ORD record
ord-4d76623545aa44dc9a388b16066efd4a
Source dataset
uspto-grants-2013_12
Patent number
US08614212B2

Reaction notes

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